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Article

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

26 Apr 2017

Abstract excerpt

Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. We examined inter-individual DNA methylation differences in human birth tissues associated with child's adiposity. We identified a novel association between the level of CpG methylation at birth within the promoter of the long non-coding RNA ANRIL (encoded at CDKN2A) and childhood adiposity...

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Share to Adipose Tissue and Metabolism
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PMID: 28473239
DOI: 10.1016/j.ebiom.2017.03.037

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