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Article

DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight.

Clinical epigenetics - 23 Mar 2023

Cameron Vicky A, Jones Gregory T, Horwood L John, Pilbrow Anna P, Martin Julia, Frampton Chris, Ip Wendy T, Troughton Richard W, Greer Charlotte, Yang Jun, Epton Michael J, Harris Sarah L, Darlow Brian A

Abstract excerpt

BACKGROUND: Individuals born very low birthweight (VLBW) are at increased risk of impaired cardiovascular and respiratory function in adulthood. To identify markers to predict future risk for VLBW individuals, we analyzed DNA methylation at birth and at 28 years in the New Zealand (NZ) VLBW cohort (all infants born < 1500 g in NZ in 1986) compared with age-matched, normal birthweight controls. Associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36959629
DOI: 10.1186/s13148-023-01463-3
PMCID: PMC10035230

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