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Article

Epigenetic mechanisms in heart development and disease.

Drug discovery today - 1 Jul 2015

Martinez Shannalee R, Gay Maresha S, Zhang Lubo

Abstract excerpt

Suboptimal intrauterine development has been linked to predisposition to cardiovascular disease in adulthood, a concept termed 'developmental origins of health and disease'. Although the exact mechanisms underlying this developmental programming are unknown, a growing body of evidence supports the involvement of epigenetic regulation. Epigenetic mechanisms such as DNA methylation, histone modifications and...

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Identifiers

PMID: 25572405
DOI: 10.1016/j.drudis.2014.12.018
PMCID: PMC4492921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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