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Article

Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

8 Jan 2019

Abstract excerpt

BACKGROUND: The early life environment may influence susceptibility to obesity and metabolic disease in later life through epigenetic processes. SLC6A4 is an important mediator of serotonin bioavailability, and has a key role in energy balance. We tested the hypothesis that methylation of the SLC6A4 gene predicts adiposity across the life course. METHODS: DNA methylation at 5 CpGs within the SLC6A4 gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30622309
DOI: 10.1038/s41366-018-0254-3

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