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Article

Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction

17 Nov 2011

Abstract excerpt

BACKGROUND: Human epidemiological studies suggest that small size at birth and food deprivation during gestation confer an excess risk of coronary heart diseases (CHD) in adulthood, frequently in a sex-specific manner. Prior epigenetic studies indicate that such prenatal conditions are marked by persistent and sometimes sex-specific changes in DNA methylation. Here, we have investigated the association between...

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PMID: 22101166
DOI: 10.1093/ije/dyr153

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