Modification of epigenetic patterns in low birth weight children: importance of hypomethylation of the ACE gene promoter.

doi:10.1371/journal.pone.0106138

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Article

Modification of epigenetic patterns in low birth weight children: importance of hypomethylation of the ACE gene promoter.

PloS one - 1 Jan 2014

Rangel Marina, dos Santos Jéssica Cassilla, Ortiz Paula Helena Lima, Hirata Mario, Jasiulionis Miriam Galvonas, Araujo Ronaldo C, Ierardi Daniela Filippini, Franco Maria do Carmo

Abstract excerpt

There is a growing body of evidence that epigenetic alterations are involved in the pathological mechanisms of many chronic disorders linked to fetal programming. Angiotensin-converting enzyme (ACE) appears as one candidate gene that brings new insights into the epigenetic control and later development of diseases. In this view, we have postulated that epigenetic modifications in the ACE gene might show different...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25170764
DOI: 10.1371/journal.pone.0106138
PMCID: PMC4149513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.