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Article

Aberrant DNA methylation at genes associated with a stem cell-like phenotype in cholangiocarcinoma tumors.

Cancer prevention research (Philadelphia, Pa.) - 1 Dec 2013

Sriraksa Ruethairat, Zeller Constanze, Dai Wei, Siddiq Afshan, Walley Andrew J, Limpaiboon Temduang, Brown Robert

Abstract excerpt

Genetic abnormalities of cholangiocarcinoma have been widely studied; however, epigenomic changes related to cholangiocarcinogenesis have been less well characterized. We have profiled the DNA methylomes of 28 primary cholangiocarcinoma and six matched adjacent normal tissues using Infinium's HumanMethylation27 BeadChips with the aim of identifying gene sets aberrantly and epigenetically regulated in this tumor...

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Source

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Identifiers

PMID: 24089088
DOI: 10.1158/1940-6207.CAPR-13-0104
PMCID: PMC3855864

Genes

EED
HOXA9
HOXD9
SUZ12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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