Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Global Alterations of DNA Methylation in Cholangiocarcinoma Target the Wnt Signaling Pathway

3 Sept 2013

Abstract excerpt

UNLABELLED: The molecular mechanisms underlying the genesis of cholangiocarcinomas (CCs) are poorly understood. Epigenetic changes such as aberrant hypermethylation and subsequent atypical gene expression are characteristic features of most human cancers. In CC, data regarding global methylation changes are lacking so far. We performed a genome-wide analysis for aberrant promoter methylation in human CCs. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Epigenetics and DNA Methylation
Share to Gallbladder and Bile Duct Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24002901
DOI: 10.1002/hep.26721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global Alterations of DNA Methylation in Cholangiocarcinoma Target the Wnt Signaling PathwayPMID 24002901Read ↗

Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.Semantic proximity Read ↗

Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinomaSemantic proximity Read ↗

Novel target genes and a valid biomarker panel identified for cholangiocarcinomaSemantic proximity Read ↗

Comprehensive analysis of DNA methylation and gene expression profiles in cholangiocarcinomaSemantic proximity Read ↗

Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targetsSemantic proximity Read ↗

Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinomaSemantic proximity Read ↗

Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinomaSemantic proximity Read ↗

Aberrant DNA Methylation as a Biomarker and a Therapeutic Target of CholangiocarcinomaSemantic proximity Read ↗

Aberrant DNA Methylation in CholangiocarcinomaSemantic proximity Read ↗

Genetic and epigenetic changes associated with cholangiocarcinoma: From DNA methylation to microRNAsSemantic proximity Read ↗

The DNA methylome of benign and malignant parathyroid tumorsSemantic proximity Read ↗

The roles of epigenetic regulation in cholangiocarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.