Article
Impact of deletions and mutations in Hepatitis B virus envelope proteins on serological profile and clinical evolution.
Virus research - 15 Jun 2017
Malve Brice, Eschlimann Marine, Galgey Shaunagh, Fenaux Honorine, Zoulim Fabien, Goehringer François, Rabaud Christian, May Thierry, Jeulin Hélène, Schvoerer Evelyne
Abstract excerpt
The Hepatitis B virus (HBV) envelope glycoproteins are essential for viral entry into the hepatocyte and are also targets for host immune response. The study of these proteins could allow us to highlight molecular hot points influencing HBV fitness, which would subsequently modify the clinical evolution of the disease, both under anti-viral therapy or without treatment. The present short communication underlines...
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