Article
Characterization of naturally occurring and Lamivudine-induced surface gene mutants of hepatitis B virus in patients with chronic hepatitis B in India.
Intervirology - 1 Jan 2006
Kazim Syed Naqui, Sarin Shiv Kumar, Sharma Barjesh Chander, Khan Luqman Ahmad, Hasnain Seyed Ehtesham
Abstract excerpt
BACKGROUND: Besides vaccine escape or immune escape hepatitis B virus (HBV) mutants, naturally occurring and drug-induced mutations have been reported in the surface gene (S-gene) of HBV. AIM: To investigate the frequency and profile of naturally occurring S-gene mutants and the influence of long-term lamivudine therapy in patients with chronic hepatitis B (CHB). MATERIALS AND METHODS: 57 patients with...
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