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Article

Analysis of entire hepatitis B virus genomes reveals reversion of mutations to wild type in natural infection, a 15 year follow-up study.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2022

Chen Qin-Yan, Jia Hui-Hua, Wang Xue-Yan, Shi Yun-Liang, Zhang Lu-Juan, Hu Li-Ping, Wang Chao, He Xiang, Harrison Tim J, Jackson J Brooks, Wu Li, Fang Zhong-Liao

Abstract excerpt

It has been reported that some mutations in the genome of hepatitis B virus (HBV) may predict the outcome of the virus infection. However, evolutionary data derived from long-term longitudinal analysis of entire HBV genomes using next generation sequencing (NGS) remain rare. In this study, serum samples were collected from asymptomatic hepatitis B surface antigen (HBsAg) carriers from a long-term prospective...

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Identifiers

PMID: 34902556
DOI: 10.1016/j.meegid.2021.105184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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