Article
The Impact of HBV Quasispecies Features on Immune Status in HBsAg+/HBsAb+ Patients With HBV Genotype C Using Next-Generation Sequencing.
Frontiers in immunology - 1 Jan 2021
Wang Ying, Xiao Xiao, Chen Shipeng, Huang Chenjun, Zhou Jun, Dai Erhei, Li Ya, Liu Lijuan, Huang Xianzhang, Gao Zhiyuan, Wu Chuanyong, Fang Meng, Gao Chunfang
Abstract excerpt
Background: This study aimed to explore the molecular mechanism of the coexistence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb) serological pattern via intensive characterization of HBV s gene in both chronic hepatitis B (CHB) and hepatocellular carcinoma (HCC) patients. Method: A total of 73 HBsAg+/HBsAb+ patients (CHB = 36, HCC = 37) and 96 HBsAg+/HBsAb- patients (CHB = 47,...
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