Article
Impaired Lymphocytes Development and Xenotransplantation of Gastrointestinal Tumor Cells in Prkdc-Null SCID Zebrafish Model.
Neoplasia (New York, N.Y.) - 1 Aug 2016
Jung In Hye, Chung Yong-Yoon, Jung Dawoon E, Kim Young Jin, Kim Do Hee, Kim Kyung-Sik, Park Seung Woo
Abstract excerpt
Severe combined immunodeficiency (SCID) mice have widely been used as hosts for human tumor cell xenograft study. This animal model, however, is labor intensive. As zebrafish is largely emerging as a promising model system for studying human diseases including cancer, developing efficient immunocompromised strains for tumor xenograft study are also demanded in zebrafish. Here, we have created the Prkdc-null SCID...
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