Article
Rapid growth and spontaneous metastasis of human germinal tumors ectopically transplanted into scid (severe combined immunodeficiency) and scid-nudestreaker mice.
Japanese journal of cancer research : Gann - 1 Jun 1991
Nomura T, Takahama Y, Hongyo T, Takatera H, Inohara H, Fukushima H, Ono S, Hamaoka T
Abstract excerpt
Xenograft acceptance, growth and spontaneous metastasis of ectopically transplanted human germinal tumors were compared among scid mice, athymic nude mice and F2 hybrids constructed from scid and nude mice, in relation to the impairments of T and B cell functions in these mice. In scid mice which are deficient in T and B cell functions, human yolk sac tumor (YST-2) that originated from the ovary grew to enormous...
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