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Article

The SCID mouse mutant: definition, characterization, and potential uses.

Annual review of immunology - 1 Jan 1991

Bosma M J, Carroll A M

Abstract excerpt

Mice homozygous for the scid mutation (scid mice) are severely deficient in functional B and T lymphocytes. The mutation appears to impair the recombination of antigen receptor genes and thereby causes an arrest in the early development of B and T lineage-committed cells; other hematopoietic cell...

Topics

Animals
Chromosome Mapping
Gene Rearrangement
Humans
Immunologic Deficiency Syndromes
Lymphocyte Transfusion
Lymphocytes
Mice
Mice, Mutant Strains
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1910681
DOI: 10.1146/annurev.iy.09.040191.001543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1910681-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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