Article

Application of Highly Immunocompromised Mice for Establishment of Patient-Derived Xenograft (PDX) Model

2019-06-03

Abstract excerpt

Patient-derived xenograft (PDX) models are created by engraftment of patients’ tumor tissues into immunocompetent mice. Since PDX model keep the characteristics of primary patient’s tumor such as gene expression profiles and drug sensitivity, it now becomes most reliable in vivo human cancer model. The engraftment rate are increased with the introduction of NOD/Scid based immunocompromised mice, especi...

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Literature Corpus work: fb3eefa3-38db-5190-b6c6-a491dde51965
DOI: 10.20944/preprints201906.0002.v1

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