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Article

Polymorphisms within the COL5A1 gene and regulators of the extracellular matrix modify the risk of Achilles tendon pathology in a British case-control study.

Journal of sports sciences - 1 Aug 2017

Brown Karryn L, Seale Kirsten B, El Khoury Louis Y, Posthumus Michael, Ribbans William J, Raleigh Stuart M, Collins Malcolm, September Alison V

Abstract excerpt

Several genetic loci have been associated with risk of Achilles tendon pathology (ATP) within South African and Australian populations. The aim of this study was, therefore, to evaluate eight previously implicated genetic variants in an independent British population. A total of 130 asymptomatic controls (CON) and 112 participants clinically diagnosed with ATP comprising 87 individuals with chronic Achilles...

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Identifiers

PMID: 27541197
DOI: 10.1080/02640414.2016.1221524

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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