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Article

Extracellular matrix proteins interact with cell-signaling pathways in modifying risk of achilles tendinopathy.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jun 2015

Saunders Colleen J, van der Merwe Lize, Cook Jill, Handley Christopher J, Collins Malcolm, September Alison V

Abstract excerpt

The aim of this study was to investigate interactions between variants within genes encoding components of the collagen fibril and components of cell-signaling pathways within the extracellular matrix, and determine the relative contribution of these variants to Achilles tendinopathy risk in a polygenic model. A total of 339 asymptomatic control participants and 179 participants clinically diagnosed with Achilles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25640225
DOI: 10.1002/jor.22820

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CASP8

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