Article
Association of type XI collagen genes with chronic Achilles tendinopathy in independent populations from South Africa and Australia.
British journal of sports medicine - 1 Jun 2013
Hay Melanie, Patricios Jon, Collins Robert, Branfield Andy, Cook Jill, Handley Christopher J, September Alison V, Posthumus Michael, Collins Malcolm
Abstract excerpt
BACKGROUND: Type XI collagen, which is expressed in developing tendons and is encoded by the COL11A1, COL11A2 and COL2A1 genes, shares structural and functional homology with type V collagen, which plays an important role in collagen fibril assembly. We investigated the association of these three polymorphisms with Achilles tendinopathy (AT) and whether these polymorphisms interact with COL5A1 to modulate the...
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