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Article

A family-based study of gene variants and maternal folate and choline in neuroblastoma: a report from the Children's Oncology Group.

Cancer causes & control : CCC - 1 Oct 2016

Mazul Angela L, Siega-Riz Anna Maria, Weinberg Clarice R, Engel Stephanie M, Zou Fei, Carrier Kathryn S, Basta Patricia V, Vaksman Zalman, Maris John M, Diskin Sharon J, Maxen Charlene, Naranjo Arlene, Olshan Andrew F

Abstract excerpt

PURPOSE: Neuroblastoma is a childhood cancer of the sympathetic nervous system with embryonic origins. Previous epidemiologic studies suggest maternal vitamin supplementation during pregnancy reduces the risk of neuroblastoma. We hypothesized offspring and maternal genetic variants in folate-related and choline-related genes are associated with neuroblastoma and modify the effects of maternal intake of folate,...

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PMID: 27541142
DOI: 10.1007/s10552-016-0799-1
PMCID: PMC5025391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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