Article
Reduced folate carrier-1 G80a gene polymorphism is associated with neuroblastoma's development.
Molecular biology reports - 1 Aug 2014
de Miranda Dyego O, Barros Jemima E X S, Vieira Maria Madalena S, Lima Elker L S, Moraes Vera L L, da Silva Helker A, Garcia Helder L B O, Lima Cássia A, Gomes Adriana V, Santos Neide, Muniz Maria T C
Abstract excerpt
Neuroblastoma is a malignant embryonal tumor of neural crest cells that give rise to the sympathetic nervous system, responsible for 10-70% of all cases of childhood cancer. Because of its early appearance, it has been suggested that risk factors active in the prenatal can be associated with the pathogenesis of neuroblastoma. The aim of this study was to investigate whether the genetic polymorphisms MTHFR C677T...
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