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Article

Associations of folate and choline metabolism gene polymorphisms with orofacial clefts.

Journal of medical genetics - 1 Dec 2010

Mostowska Adrianna, Hozyasz Kamil K, Wojcicki Piotr, Dziegelewska Maja, Jagodzinski Pawel P

Abstract excerpt

BACKGROUND: Non-syndromic isolated cleft lip with or without cleft palate (NCL/P) is a common congenital anomaly in humans, the aetiology of which is complex and associated with both genetic and environmental factors. It has been reported that maternal nutritional factors are likely to play a major role in development of NCL/P in the embryo. OBJECTIVE: As the mechanism by which folic acid and choline...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19737740
DOI: 10.1136/jmg.2009.070029

Genes

NCL
BHMT
MTHFR
MTR
PEMT
BHMT2
CBS
CHDH
CHKA
MTHFD1
MTRR
TCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Associations of folate and choline metabolism gene polymorphisms with orofacial clefts.PMID 19737740Read ↗

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