Article
Folate pathway and nonsyndromic cleft lip and palate.
Birth defects research. Part A, Clinical and molecular teratology - 1 Jan 2011
Blanton Susan H, Henry Robin R, Yuan Quiping, Mulliken John B, Stal Samuel, Finnell Richard H, Hecht Jacqueline T
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (NSCLP) is a common complex birth defect. Periconceptional supplementation with folic acid, a key component in DNA synthesis and cell division, has reduced the birth prevalence of neural tube defects and may similarly reduce the birth prevalence of other complex birth defects including NSCLP. Past studies investigating the role of two common...
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