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Article

Genetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance.

BMC medicine - 16 Aug 2016

Satta Giovanni, Witney Adam A, Shorten Robert J, Karlikowska Magdalena, Lipman Marc, McHugh Timothy D

Abstract excerpt

BACKGROUND: The largest outbreak of isoniazid-resistant (INH-R) Mycobacterium tuberculosis in Western Europe is centred in North London, with over 400 cases diagnosed since 1995. In the current study, we evaluated the genetic variation in a subset of clinical samples from the outbreak with the hypothesis that these isolates have unique biological characteristics that have served to prolong the outbreak. METHODS:...

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Identifiers

PMID: 27530812
DOI: 10.1186/s12916-016-0659-6
PMCID: PMC4988016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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