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Article

Comprehensive genomic analysis of Mycobacterium tuberculosis reveals limited impact of high-fitness genotypes on MDR-TB transmission.

The Journal of infection - 1 Jul 2022

Chen Yiwang, Liu Qingyun, Takiff Howard E, Gao Qian

Abstract excerpt

OBJECTIVES: Environmental and host-related factors that contribute to the transmission of multidrug-resistant tuberculosis (MDR-TB) have become an increasing concern, but the impact of bacterial genetic factors associated with bacterial fitness on MDR-TB transmission is poorly understood. Here, we present a global view of the correlation between common fitness-related genotypes and MDR-TB transmission by...

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PMID: 35588941
DOI: 10.1016/j.jinf.2022.05.012

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