Article
Genomic stability over 9 years of an isoniazid resistant Mycobacterium tuberculosis outbreak strain in Sweden.
PloS one - 31 Jan 2011
Sandegren Linus, Groenheit Ramona, Koivula Tuija, Ghebremichael Solomon, Advani Abdolreza, Castro Elsie, Pennhag Alexandra, Hoffner Sven, Mazurek Jolanta, Pawlowski Andrzej, Kan Boris, Bruchfeld Judith, Melefors Öjar, Källenius Gunilla
Abstract excerpt
In molecular epidemiological studies of drug resistant Mycobacterium tuberculosis (TB) in Sweden a large outbreak of an isoniazid resistant strain was identified, involving 115 patients, mainly from the Horn of Africa. During the outbreak period, the genomic pattern of the outbreak strain has stayed virtually unchanged with regard to drug resistance, IS6110 restriction fragment length polymorphism and...
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