Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of the Wnt signaling pathway as predictors of aggressive disease and reclassification in men with early stage prostate cancer on active surveillance.

Carcinogenesis - 1 Oct 2016

Shu Xiang, Ye Yuanqing, Gu Jian, He Yonggang, Davis John W, Thompson Timothy C, Logothetis Christopher J, Kim Jeri, Wu Xifeng

Abstract excerpt

Little is known about the genetic predictors of prostate cancer aggressiveness and reclassification in men with localized prostate cancer undergoing active surveillance. The Wnt signaling pathway is important for prostate cancer development and progression. Identifying genetic variants associated with prostate cancer aggressiveness and reclassification may have a potential role in the management of localized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Casein Kinase II
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Invasiveness

Share to Neoplasm Proteins

Share to Neoplasm Staging

Share to Prostatic Neoplasms

Share to Risk Factors

Share to Wnt Signaling Pathway

Source

Open in PubMed Open full text

Identifiers

PMID: 27515962
DOI: 10.1093/carcin/bgw082
PMCID: PMC5035398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of the Wnt signaling pathway as predictors of aggressive disease and reclassification in men with early stage prostate cancer on active surveillance.PMID 27515962Read ↗

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases.Semantic proximity Read ↗

The prostate cancer susceptibility variant rs2735839 near KLK3 gene is associated with aggressive prostate cancer and can stratify gleason score 7 patients.Semantic proximity Read ↗

SFRP4 gene expression is increased in aggressive prostate cancerSemantic proximity Read ↗

Fine-mapping of prostate cancer aggressiveness loci on chromosome 7q22-35.Semantic proximity Read ↗

New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort.Semantic proximity Read ↗

Associations of the Expression Levels and Risk Variants of CDKN2B-AS1 Long Noncoding RNA With the Susceptibility and Progression of Prostate Cancer.Semantic proximity Read ↗

Genetic variants in epithelial-mesenchymal transition genes as predictors of clinical outcomes in localized prostate cancer.Semantic proximity Read ↗

Germline Mutations in the Kallikrein 6 Region and Predisposition for Aggressive Prostate Cancer.Semantic proximity Read ↗

Association analysis of Wnt pathway genes on prostate-specific antigen recurrence after radical prostatectomy.Semantic proximity Read ↗

Genetic Factors Associated with Prostate Cancer Conversion from Active Surveillance to TreatmentSemantic proximity Read ↗

Associations Between iCOGS Single Nucleotide Polymorphisms and Upgrading in Both Surgical and Active Surveillance Cohorts of Men with Prostate Cancer.Semantic proximity Read ↗

Genome-wide association study identifies a genetic variant associated with risk for more aggressive prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.