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Article

SFRP4 gene expression is increased in aggressive prostate cancer

23 Oct 2017

Abstract excerpt

Increased knowledge of the molecular differences between indolent and aggressive prostate cancer is needed for improved risk stratification and treatment selection. Secreted frizzled-related protein 4 (SFRP4) is a modulator of the cancer-associated Wnt pathway, and previously suggested as a potential marker for prostate cancer aggressiveness. In this study, we investigated and validated the association between...

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Share to Cancer-related gene regulation
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Share to Wnt/β-catenin signaling in development and cancer

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PMID: 29079735
DOI: 10.1038/s41598-017-14622-3

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