Article
Genome-wide association study identifies a genetic variant associated with risk for more aggressive prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2011
FitzGerald Liesel M, Kwon Erika M, Conomos Matthew P, Kolb Suzanne, Holt Sarah K, Levine David, Feng Ziding, Ostrander Elaine A, Stanford Janet L
Abstract excerpt
BACKGROUND: Of the 200,000 U.S. men annually diagnosed with prostate cancer, approximately 20% to 30% will have clinically aggressive disease. Although factors such as Gleason score and tumor stage are used to assess prognosis, there are no biomarkers to identify men at greater risk for developing aggressive prostate cancer. We therefore undertook a search for genetic variants associated with risk of more...
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