Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations Between iCOGS Single Nucleotide Polymorphisms and Upgrading in Both Surgical and Active Surveillance Cohorts of Men with Prostate Cancer.

European urology - 1 Feb 2016

Kearns James T, Lapin Brittany, Wang Edward, Roehl Kimberly A, Cooper Phillip, Catalona William J, Helfand Brian T

Abstract excerpt

BACKGROUND: Associations have been documented recently between some of the 23 single nucleotide polymorphisms newly discovered with the Collaborative Oncological Gene-environment Study iCOGS array that indicate prostate cancer (PCa) risk and aspects of disease aggressiveness. The utility of these iCOGS SNPs remains to be determined in active surveillance (AS). OBJECTIVE: To determine associations between iCOGS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Neoplasm Grading

Share to Oligonucleotide Array Sequence Analysis

Share to Polymorphism, Single Nucleotide

Share to Prostatectomy

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 26411806
DOI: 10.1016/j.eururo.2015.09.004
PMCID: PMC4885743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations Between iCOGS Single Nucleotide Polymorphisms and Upgrading in Both Surgical and Active Surveillance Cohorts of Men with Prostate Cancer.PMID 26411806Read ↗

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases.Semantic proximity Read ↗

The use of exome genotyping to predict pathological Gleason score upgrade after radical prostatectomy in low-risk prostate cancer patients.Semantic proximity Read ↗

Association Between a 22-feature Genomic Classifier and Biopsy Gleason Upgrade During Active Surveillance for Prostate CancerSemantic proximity Read ↗

The prostate cancer susceptibility variant rs2735839 near KLK3 gene is associated with aggressive prostate cancer and can stratify gleason score 7 patients.Semantic proximity Read ↗

New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort.Semantic proximity Read ↗

Genome-wide association study identifies a genetic variant associated with risk for more aggressive prostate cancer.Semantic proximity Read ↗

Genetic variants of the Wnt signaling pathway as predictors of aggressive disease and reclassification in men with early stage prostate cancer on active surveillance.Semantic proximity Read ↗

Genome-wide detection of allelic genetic variation to predict advanced-stage prostate cancer after radical prostatectomy using an exome SNP chip.Semantic proximity Read ↗

Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.Semantic proximity Read ↗

Genetic Factors Associated with Prostate Cancer Conversion from Active Surveillance to TreatmentSemantic proximity Read ↗

Prostate cancer susceptibility variants confer increased risk of disease progression.Semantic proximity Read ↗

Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.