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Article

The prostate cancer susceptibility variant rs2735839 near KLK3 gene is associated with aggressive prostate cancer and can stratify gleason score 7 patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2014

He Yonggang, Gu Jian, Strom Sara, Logothetis Christopher J, Kim Jeri, Wu Xifeng

Abstract excerpt

PURPOSE: Gleason score (GS) 7 prostate cancer is a heterogeneous disease with different clinical behavior. We sought to identify genetic biomarkers that may predict the aggressiveness of GS 7 diseases. EXPERIMENTAL DESIGN: We genotyped 72 prostate cancer susceptibility SNPs identified in genome-wide association studies in 1,827 white men with histologically confirmed prostate adenocarcinoma. SNPs associated with...

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Identifiers

PMID: 25274378
DOI: 10.1158/1078-0432.CCR-14-0661
PMCID: PMC4185411

Genes

KLK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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