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Article

Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid.

Human genetics - 1 Nov 2022

Piekos Jacqueline A, Hellwege Jacklyn N, Zhang Yanfei, Torstenson Eric S, Jarvik Gail P, Dikilitas Ozan, Kullo Iftikhar J, Schaid Daniel J, Crosslin David R, Pendergrass Sarah A, Lee Ming Ta Michael, Roden Dan, Denny Josh C, Edwards Todd L, Velez Edwards Digna R

Abstract excerpt

Uterine fibroids (UF) are common pelvic tumors in women, heritable, and genome-wide association studies (GWAS) have identified ~ 30 loci associated with increased risk in UF. Using summary statistics from a previously published UF GWAS performed in a non-Hispanic European Ancestry (NHW) female subset from the Electronic Medical Records and Genomics (eMERGE) Network, we constructed a polygenic risk score (PRS) for...

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Identifiers

PMID: 35226188
DOI: 10.1007/s00439-022-02442-z
PMCID: PMC9420161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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