Article
RWCFusion: identifying phenotype-specific cancer driver gene fusions based on fusion pair random walk scoring method.
Oncotarget - 20 Sept 2016
Zhao Jianmei, Li Xuecang, Yao Qianlan, Li Meng, Zhang Jian, Ai Bo, Liu Wei, Wang Qiuyu, Feng Chenchen, Liu Yuejuan, Bai Xuefeng, Song Chao, Li Shang, Li Enmin, Xu Liyan, Li Chunquan
Abstract excerpt
While gene fusions have been increasingly detected by next-generation sequencing (NGS) technologies based methods in human cancers, these methods have limitations in identifying driver fusions. In addition, the existing methods to identify driver gene fusions ignored the specificity among different cancers or only considered their local rather than global topology features in networks. Here, we proposed a novel...
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