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Article

TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury.

Journal of medical genetics - 1 Nov 2004

Barber R C, Aragaki C C, Rivera-Chavez F A, Purdue G F, Hunt J L, Horton J W

Abstract excerpt

CONTEXT: Sepsis, organ failure, and shock remain common among patients with moderate to severe burn injuries. The inability of clinical factors to identify at-risk patients suggests that genetic variation may influence the risk for serious infection and the outcome from severe injury. OBJECTIVE: Resolution of genetic variants associated with severe sepsis following burn injury. PATIENTS: A total of 159 patients...

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Source

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Identifiers

PMID: 15520404
DOI: 10.1136/jmg.2004.021600
PMCID: PMC1383768

Genes

TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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