Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic predisposition for development of complications in multiple trauma patients.

Shock (Augusta, Ga.) - 1 May 2011

Hildebrand Frank, Mommsen Philipp, Frink Michael, van Griensven Martijn, Krettek Christian

Abstract excerpt

The care of multiple trauma patients has been improved through advances made in preclinical treatment, surgical procedures, and intensive care medicine. However, posttraumatic complications such as systemic inflammatory response syndrome, multiple organ dysfunction syndrome, and sepsis remain a major problem following multiple trauma. Components of the innate immune system and other inflammatory mediators (e.g.,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Hyperglycemia and glycemic control in critically ill and hospitalized patients

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immune Response and Inflammation

Share to Immunity, Innate

Share to Polymorphism, Single Nucleotide

Share to Sepsis Diagnosis and Treatment

Source

Identifiers

PMID: 21263379
DOI: 10.1097/SHK.0b013e31820e2152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic predisposition for development of complications in multiple trauma patients.PMID 21263379Read ↗

The genetic predisposition to adverse outcome after trauma.Semantic proximity Read ↗

Genetic predisposition for a compromised immune system after multiple trauma.Semantic proximity Read ↗

Effects of Sequence Variations in Innate Immune Response Genes on Infectious Outcome in Trauma Patients: A Comprehensive Review.Semantic proximity Read ↗

Single-nucleotide polymorphisms in the Toll-like receptor pathway increase susceptibility to infections in severely injured trauma patients.Semantic proximity Read ↗

Network Analysis of Rare Single-Nucleotide Polymorphisms Suggests a Central Role for Type 17 Immune Responses in Trauma-induced, Genotypically Associated Hypo-Inflammation and Critical IllnessSemantic proximity Read ↗

Risk of infection and sepsis in severely injured patients related to single nucleotide polymorphisms in the lectin pathway.Semantic proximity Read ↗

Rs1800625 in the receptor for advanced glycation end products gene predisposes to sepsis and multiple organ dysfunction syndrome in patients with major trauma.Semantic proximity Read ↗

Genetic susceptibility to inflammatory injury and various adverse outcomes.Semantic proximity Read ↗

Molecular analysis of inflammatory markers in trauma patients at risk of postinjury complications.Semantic proximity Read ↗

Detecting genetic predisposition for complicated clinical outcomes after burn injury.Semantic proximity Read ↗

Genetic variants in TNFA, LTA, TLR2 and TLR4 genes and risk of sepsis in patients with severe trauma: nested case-control study in a level-1 trauma centre in SERBIA.Semantic proximity Read ↗

Genetic variation in complement component 2 of the classical complement pathway is associated with increased mortality and infection: a study of 627 patients with trauma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.