Article
ClpP-deletion impairs the virulence of Legionella pneumophila and the optimal translocation of effector proteins.
BMC microbiology - 2 Aug 2016
Zhao Bei-Bei, Li Xiang-Hui, Zeng Yong-Lun, Lu Yong-Jun
Abstract excerpt
BACKGROUND: The opportunistic bacterial pathogen Legionella pneumophila uses substrate effectors of Dot/Icm type IVB secretion system (T4BSS) to accomplish survival and replication in amoebae cells and mammalian alveolar macrophages. During the conversion between its highly resistant, infectious dormant form and vigorously growing, uninfectious replicative form, L. pneumophila utilizes a complicated regulatory...
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