Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diagnostic Detection of Allelic Losses and Imbalances by Next-Generation Sequencing: 1p/19q Co-Deletion Analysis of Gliomas.

The Journal of molecular diagnostics : JMD - 1 Sept 2016

Dubbink Hendrikus J, Atmodimedjo Peggy N, van Marion Ronald, Krol Niels M G, Riegman Peter H J, Kros Johan M, van den Bent Martin J, Dinjens Winand N M

Abstract excerpt

Cancer cells are genomically unstable and accumulate tumor type-specific molecular aberrations, which may represent hallmarks for predicting prognosis and targets for therapy. Co-deletion of chromosomes 1p and 19q marks gliomas with an oligodendroglioma component and predicts a better prognosis and response to chemotherapy. In the current study, we present a novel method to detect chromosome 1p/19q co-deletion or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allelic Imbalance
Share to Autopsy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Neoplasms

Share to Chromosomes, Human, Pair 1

Share to Chromosomes, Human, Pair 19

Share to Glioma

Share to Loss of Heterozygosity

Share to Sequence Deletion

Source

Identifiers

PMID: 27461031
DOI: 10.1016/j.jmoldx.2016.06.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diagnostic Detection of Allelic Losses and Imbalances by Next-Generation Sequencing: 1p/19q Co-Deletion Analysis of Gliomas.PMID 27461031Read ↗

Utility of targeted next-generation sequencing assay to detect 1p/19q co-deletion in formalin-fixed paraffin-embedded glioma specimens.Semantic proximity Read ↗

Genomic changes in gliomas detected using single nucleotide polymorphism array in formalin-fixed, paraffin-embedded tissue: superior results compared with microsatellite analysis.Semantic proximity Read ↗

Detection of chromosome structural variation by targeted next-generation sequencing and a deep learning applicationSemantic proximity Read ↗

Loss of heterozygosity analysis in malignant gliomas.Semantic proximity Read ↗

Design and Validation of a Gene-Targeted, Next-Generation Sequencing Panel for Routine Diagnosis in GliomasSemantic proximity Read ↗

Absence of common somatic alterations in genes on 1p and 19q in oligodendrogliomas.Semantic proximity Read ↗

Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing.Semantic proximity Read ↗

FISH-based detection of 1p 19q codeletion in oligodendroglial tumors: procedures and protocols for neuropathological practice – a publication under the auspices of the Research Committee of the European Confederation of Neuropathological Societies (Semantic proximity Read ↗

Molecular profiling of oligodendrogliomas: impact on prognosis, treatment, and future directions.Semantic proximity Read ↗

A custom next-generation sequencing panel for 1p/19q codeletion and mutational analysis in gliomas.Semantic proximity Read ↗

Next-Generation Sequencing Panel for 1p/19q Codeletion and IDH1-IDH2 Mutational Analysis Uncovers Mistaken Overdiagnoses of 1p/19q Codeletion by FISH.Semantic proximity Read ↗

The role of MGMT testing in clinical practice: a report of the association for molecular pathology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.