Article
The role of MGMT testing in clinical practice: a report of the association for molecular pathology.
The Journal of molecular diagnostics : JMD - 1 Sept 2013
Cankovic Milena, Nikiforova Marina N, Snuderl Matija, Adesina Adekunle M, Lindeman Neal, Wen Patrick Y, Lee Eudocia Q
Abstract excerpt
Recent advances in modern molecular technologies allow for the examination and measurement of cancer-related genomic changes. The number of molecular tests for evaluation of diagnostic, prognostic, or predictive markers is expected to increase. In recent years, O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation has been firmly established as a biomarker in patients diagnosed with gliomas, for...
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