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Article

Absence of common somatic alterations in genes on 1p and 19q in oligodendrogliomas.

PloS one - 1 Jan 2011

Bralten Linda B, Nouwens Stephan, Kockx Christel, Erdem Lale, Hoogenraad Casper C, Kros Johan M, Moorhouse Michael J, Sillevis Smitt Peter A, van der Spek Peter, van Ijcken Wilfred, Stubbs Andrew, French Pim J

Abstract excerpt

A common and histologically well defined subtype of glioma are the oligodendroglial brain tumors. Approximately 70% of all oligodendrogliomas have a combined loss of the entire 1p and 19q chromosomal arms. This remarkably high frequency suggests that the remaining arms harbor yet to be identified tumor suppressor genes. Identification of these causal genetic changes in oligodendrogliomas is important because they...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21760942
DOI: 10.1371/journal.pone.0022000
PMCID: PMC3131305

Genes

ARHGEF16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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