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Article

Loss of heterozygosity analysis in malignant gliomas.

Brain tumor pathology - 1 Jul 2011

Mizoguchi Masahiro, Kuga Daisuke, Guan Yanlei, Hata Nobuhiro, Nakamizo Akira, Yoshimoto Koji, Sasaki Tomio

Abstract excerpt

Despite recent advances in the diagnosis and treatment of glioblastomas, patient outcomes for these highly malignant tumors remain poor. Research into the molecular pathology of glioblastoma has uncovered various genetic changes that contribute to malignancy. Some of the identified molecular markers--such as loss of heterozygosity (LOH) on chromosome 1p/19q and chromosome 10, O6-methylguanine methyltransferase...

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PMID: 21629980
DOI: 10.1007/s10014-011-0038-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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