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Utility of targeted next-generation sequencing assay to detect 1p/19q co-deletion in formalin-fixed paraffin-embedded glioma specimens.

Human pathology - 1 Aug 2022

Pallavajjala Aparna, Haley Lisa, Stinnett Victoria, Adams Emily, Pallavajjala Roshni, Huang Jialing, Morsberger Laura, Hardy Melanie, Long Patty, Gocke Christopher D, Eshleman James R, Rodriguez Fausto J, Zou Ying S

Abstract excerpt

Molecular classification of brain neoplasms is important for diagnosis, prognosis, and treatment outcome of histologically similar tumors. Oligodendroglioma is a glioma subtype characterized by 1p/19q co-deletion and IDH1/IDH2 mutations, which predict a good prognosis, responsiveness to therapy, and an improved overall survival compared to other adult gliomas. In a routine clinical setting, 1p/19q co-deletion is...

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PMID: 35561840
DOI: 10.1016/j.humpath.2022.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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