Article
Molecular profiling of oligodendrogliomas: impact on prognosis, treatment, and future directions.
Current oncology reports - 1 Jan 2009
Ney Douglas E, Lassman Andrew B
Abstract excerpt
Oligodendrogliomas account for a small subset of all gliomas, but they often are more sensitive to treatment than other glioma subtypes. In addition, oligodendrogliomas are the first central nervous system neoplasm for which a specific molecular abnormality, allelic loss of 1p/19q (1p/19q loss), correlates with patient outcome in large-scale prospective clinical trials. However, the incorporation of 1p/19q status...
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