Article
HLA-G 14-bp insertion/deletion polymorphism is a risk factor for HTLV-1 infection.
AIDS research and human retroviruses - 1 Mar 2011
Haddad Rodrigo, Cilião Alves Daiani Cristina, Rocha-Junior Maurício Cristiano, Azevedo Rochele, Pombo-de-Oliveira Maria do Socorro, Takayanagui Oswaldo Massaiti, Donadi Eduardo Antônio, Covas Dimas Tadeu, Kashima Simone
Abstract excerpt
About 95% of HTLV-1 infected patients remain asymptomatic throughout life, and the risk factors associated with the development of related diseases, such as HAM/TSP and ATL, are not fully understood. The human leukocyte antigen-G molecule (HLA-G), a nonclassical HLA class I molecule encoded by MHC, is expressed in several pathological conditions, including viral infection, and is related to immunosuppressive...
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