Article
Correlation between polymorphisms at interleukin-6 but not at interleukin-10 promoter and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in Brazilian individuals.
Journal of medical virology - 1 Dec 2008
Gadelha Sandra Rocha, Junior Alcântara Luiz Carlos, Costa Gisele Calazans, Acosta Angelina Xavier, Rios Domingos, Kashima Simone, Covas Dimas Tadeu, Galvão-Castro Bernardo
Abstract excerpt
HTLV-1 is the etiologic agent of ATL and HAM/TSP. The majority of HTLV-1-infected individuals remain asymptomatic, indicating that the infection alone is not sufficient to cause the diseases. It has been reported that cytokine gene polymorphisms, including polymorphisms at IL-6 and IL-10 gene, mi...
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