Article
Deep Sequencing Analysis of Human T Cell Lymphotropic Virus Type 1 Long Terminal Repeat 5' Region from Patients with Tropical Spastic Paraparesis/Human T Cell Lymphotropic Virus Type 1-Associated Myelopathy and Asymptomatic Carriers.
AIDS research and human retroviruses - 1 Mar 2016
Rego Filipe Ferreira de Almeida, de Oliveira Tulio, Giovanetti Marta, Galvão-Castro Bernardo, Gonçalves Marilda de Souza, Alcantara Luiz Carlos
Abstract excerpt
The aim of this study was to analyze patients by deep sequencing the human T cell lymphotropic virus type 1 (HTLV-1) long terminal repeat (LTR) region in order to determine if minor and/or major mutations in this promoter region might be associated with tropical spastic paraparesis (TSP)/human T cell lymphotropic virus type 1-associated myelopathy (HAM) outcome or proviral load or HTLV-1 expression. This study is...
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