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Article

MBASED: allele-specific expression detection in cancer tissues and cell lines.

Genome biology - 7 Aug 2014

Mayba Oleg, Gilbert Houston N, Liu Jinfeng, Haverty Peter M, Jhunjhunwala Suchit, Jiang Zhaoshi, Watanabe Colin, Zhang Zemin

Abstract excerpt

Allele-specific gene expression, ASE, is an important aspect of gene regulation. We developed a novel method MBASED, meta-analysis based allele-specific expression detection for ASE detection using RNA-seq data that aggregates information across multiple single nucleotide variation loci to obtain a gene-level measure of ASE, even when prior phasing information is unavailable. MBASED is capable of one-sample and...

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Identifiers

PMID: 25315065
DOI: 10.1186/s13059-014-0405-3
PMCID: PMC4165366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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