The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: a replication study.

doi:10.1503/jpn.140097

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Article

The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: a replication study.

Journal of psychiatry & neuroscience : JPN - 1 May 2015

Gutiérrez Blanca, Bellón Juan Á, Rivera Margarita, Molina Esther, King Michael, Marston Louise, Torres-González Francisco, Moreno-Küstner Berta, Moreno-Peral Patricia, Motrico Emma, Montón-Franco Carmen, GildeGómez-Barragán María J, Sánchez-Celaya Marta, Díaz-Barreiros Miguel Á, Vicens Catalina, de Dios Luna Juan, Nazareth Irwin, Cervilla Jorge

Abstract excerpt

BACKGROUND: There is limited evidence for a moderating role of both serotonin transporter (SERT) and brain-derived neurotrophic factor (BDNF) genes on the risk for major depression (MD) developing after childhood maltreatment. However, research on this topic remains inconclusive, and there is a lack of data from longitudinal studies with large and representative population samples. Our study aimed to clarify...

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Identifiers

PMID: 25510949
DOI: 10.1503/jpn.140097
PMCID: PMC4409436

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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