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Article

Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.

PloS one - 1 Jan 2014

Huang Liang, Hu Fang, Xie Xiaoling, Harder Jeffery, Fernandes Kimberly, Zeng Xiang-yun, Libby Richard, Gan Lin

Abstract excerpt

PURPOSE: To investigate the role of Pou4f1 and Pou4f2 in the survival of adult retinal ganglion cells (RGCs). METHODS: Conditional alleles of Pou4f1 and Pou4f2 were generated (Pou4f1loxP and Pou4f2loxP respectively) for the removal of Pou4f1 and Pou4f2 in adult retinas. A tamoxifen-inducible Cre was used to delete Pou4f1 and Pou4f2 in adult mice and retinal sections and flat mounts were subjected to...

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PMID: 24736625
DOI: 10.1371/journal.pone.0094173
PMCID: PMC3988073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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