Article
Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.
The Journal of comparative neurology - 1 Jun 2021
Parmhans Nadia, Fuller Anne Drury, Nguyen Eileen, Chuang Katherine, Swygart David, Wienbar Sophia Rose, Lin Tyger, Kozmik Zbynek, Dong Lijin, Schwartz Gregory William, Badea Tudor Constantin
Abstract excerpt
Members of the POU4F/Brn3 transcription factor family have an established role in the development of retinal ganglion cell (RGCs) types, the main transducers of visual information from the mammalian eye to the brain. Our previous work using sparse random recombination of a conditional knock-in reporter allele expressing alkaline phosphatase (AP) and intersectional genetics had identified three types of Brn3c...
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