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Article

Full and Partial Agonism of a Designed Enzyme Switch.

ACS synthetic biology - 16 Dec 2016

Budiardjo S Jimmy, Licknack Timothy J, Cory Michael B, Kapros Dora, Roy Anuradha, Lovell Scott, Douglas Justin, Karanicolas John

Abstract excerpt

Chemical biology has long sought to build protein switches for use in molecular diagnostics, imaging, and synthetic biology. The overarching challenge for any type of engineered protein switch is the ability to respond in a selective and predictable manner that caters to the specific environments and time scales needed for the application at hand. We previously described a general method to design switchable...

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Identifiers

PMID: 27389009
DOI: 10.1021/acssynbio.6b00097
PMCID: PMC5161622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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